Total number of phenotypes for which the molecular basis is known: 7,203
Total number of genes with phenotype-causing mutation: 4,656
The 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) has nearly 70,000 codes (an upper-bound disease estimate)
Of 30,000 known diseases about 6,000–7,000 are defined as rare diseases, also commonly known as orphan diseases . Within the European Union (EU), rare diseases are specified as indications with a prevalence of less than 5 out of 10,000 . – source: The European Journal of Health Economics
“FDA has approved about 552 orphan drugs. [1983-2015]” FDA law blog
Every cancer is a unique, personal disease. “Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths.” (WHO)
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Normax Biomed Ltd (Normax) is based in Cork, Ireland, and London, England. Normax is in the business of mRNA vaccine Research, Development and Manufacturing. Normax has secured a €300,000,000 capital commitment from a $3.4Bn cornerstone institutional investor for development of mRNA Vaccines and Vax Factory Manufacturing for Transformative Social Impact on Infectious Disease and Pandemic Preparedness. Normax plans to drive down the cost of mRNA Vaccines to save more lives and to deliver sustainable returns for impact investors. Normax plans to deliver safe and effective mRNA vaccines at large scale for about $4 dollars per dose. Normax mRNA vaccine products in development include: (1) mRNA Vax Factory, (2) Universal Coronavirus mRNA Vaccine, (3) Tuberculosis mRNA Vaccine, (4) HIV mRNA Vaccine, (5) Malaria mRNA Vaccine, and (6) Disease-X mRNA Vaccine (e.g. within 100 days). Normax mission is to deliver competitive financial performance with transformative social impact. NOT AN OFFER TO INVEST.
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